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Availability of greater computer power coupled with developments in robotics and availability of automated methods for sequencing large amounts of DNA allowed completion of large-scale genome sequencing projects over the last 15 years. The most famous of these is the Human Genome Project, which sequenced all the genes encoded in the 3200 million base pairs and approximately 2 m per cell of human DNA. This project was completed ahead of schedule by an eventual collaboration between a public domain academic human genome project consortium and a commercial company Celera (which means swift ) (Figure 9.5). The complete genomes of many other representative organisms are now available. The smallest genomes, those of viruses, can be <200 000 base pairs in length while the genome of Escherichia coli consists of 4.6 million base pairs. We now know the sequences of hundreds of other prokaryotes and archaebacteria. Many of these are pathogenic organisms (e.g. causative agents of bubonic plague, diphtheria, pneumonia, etc.) or species of agronomic or biotechnological importance (e.g. lactobacilli). In bacteria, the bulk of DNA encodes genes while most eukaryotic DNA is noncoding. Selected URLs devoted to genomes are listed in Table 9.2.

1.711 2.314 3.400 5.933 18.60

When you open a PDF document in an Acrobat viewer, you can invoke a Find command to search for a keyword, as shown in Figure 1-2. The viewer then searches through the pages and stops at the first occurrence of the searched word it finds (see Figure 1-3). This is fine if you have a single document open and need to search for the content within the open document. If you have several PDF files and want to search all documents for a keyword or words, you need Acrobat Search. Like Acrobat Reader, Acrobat Search is a free plug-in, and it can be used with all Acrobat viewers. Acrobat Search is a powerful search engine that goes beyond searching for keywords. You can search with operators or Boolean expressions and narrow searches to specific requirements, as I discuss in 2.

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When drawing a line, think of it as having a starting point and an ending point. After the line is drawn, however, both of these points are considered endpoints in terms of object snaps. When picking the endpoint of a line for the endpoint object snap, pick a point on the line closer to the endpoint that you want. The same applies to arcs. Although the arc prompts read Start point and End, both are considered endpoints for purposes of object snaps.

, Measurement of Wavefronts Without a Reference Standard I: The Wavefront Shearing Interferometer, J Res Nat Bur Stand, 65B, 239 (1961) Saunders J B, Wavefront Shearing Prism Interferometer, J Res Nat Bur Stand, 68C, 155 (1964a) Saunders J B, Interferometer Test of the 26-Inch Refractor at Leander McCormick Observatory, Astron J, 69, 449 (1964b)..

That s why I ve put my Windows XP Media Center Edition PC in my entertainment center cabinet It s busy acting as my TV tuner It s recording whatever I watch in real time and allowing me to pause and rewind the show I m watching I set it to record all my favorite shows I use it to listen to music I watch DVDs from it I watch and store my home movies with it And when I m not doing anything with it, it displays all of my personal photographs in a beautiful slideshow on my TV screen I don t have a computer monitor attached to it just a TV I don t even use a keyboard or a mouse with it I just use a remote control What about computing I realized that most of my real computing was done at work.

I was really using my computer at home for entertainment: burning MP3s, storing pictures from my digital camera, or making edits of my videos All of that can be done using a TV and remote control when you have a Windows XP Media Center Edition PC About the only things I don t use it for are writing e-mails and accessing the Internet I can do those things with it too I just prefer to do that at a desk using my laptop rather then from my sofa But even that habit is starting to change Owning a Windows XP Media Center Edition PC has revolutionized my living room Gone are all of the devices that used to ll shelves next to my TV The VCR, the DVD player, my TiVo, and my stereo are all now collecting dust in the closet.

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