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OA, these genetic risk factors alone are not suf cient to produce OA Fibromyalgia FM is a chronic pain syndrome of unknown origin that currently affects an estimated 37 million Americans In contrast to the physical evidence of disease processes in RA and OA, individuals with FM experience chronic musculoskeletal pain with no identi able site of pathology Despite the lack of identi able pathology, numerous researchers have attempted to understand the biological processes in FM One of the most viable models for FM is a dysregulation of neurohormonal and pain-transmitting substances in the central nervous system (CNS) (for a review, see Bennett, 1999) An imbalance of crucial pain-transmitting chemicals such as substance P (Russell et al.

EXPERT OPINIONS ON THE NATURE OF INTELLIGENCE Historically, one of the most important approaches to guring out what intelligence is has relied on the opinions of experts. Such opinions are sometimes referred to as implicit theories, to distinguish them from the more formal explicit theories that serve as the bases for scienti c hypotheses and subsequent data collections. Implicit theories (which can be those of laypersons as well as of experts) are important to the history of a eld for at least three reasons (R. J. Sternberg, Conway, Ketron, & Bernstein, 1981). First, experts implicit theories are typically what give rise to their explicit theories. Second, much of the history of intelligence research and practice is much more closely based on implicit theories than it is on formal theories. Most of the intelligence tests that have been used, for example, are based more on the opinions of their creators as to what intelligence is than on formal theories. Third, people s everyday judgments of each other s intelligence always have been and continue to be much more strongly guided by their implicit theories of intelligence than by any explicit theories.

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, 1994) and dysregulation of HPA axis activity have been documented in patients with FM (Adler, Kinsley, Hurwitz, Mossey, & Goldenberg, 1999; Bennett, 1999; Catley, Kaell, Kirschbaum, & Stone, 2000; Clauw & Chrousos, 1997) The nding that the majority of individuals with FM report nonrefreshing sleep provides further evidence for CNS dysregulation in FM (Bennett, 1993) In healthy individuals, stage 3 and 4 sleep is characterized by delta-wave activity However, results of early studies on sleep patterns in FM patients revealed that the delta-wave activity of stages 3 and 4 sleep were consistently interrupted by the alpha waves normally found in stage 1 and stage 2 (Moldofsky, Scarisbrick, England, & Smythe, 1975) Furthermore, when healthy individuals were selectively deprived of stage 4 sleep for several days, they began to complain of musculoskeletal pain and fatigue (Moldofsky & Scarisbrick, 1976).

Generation and Properties of Wood Smoke Curing smoke develops as a result of the partial burning of wood with a limited oxygen supply. Generally, hardwood is used, mainly oak and beech. However, for imparting speci c color or avor to some products, wood from other trees that are rich in resins, including coniferous, as well as heather, may be used. In some areas, other carbohydraterich material (e.g., bagasse [sugarcane], beet refuse from sugar making, or coconut husks) is used. The smoke consists of gaseous products of thermal degradation and subsequent partial oxidation of the wooden material and of the dispersed soot and compounds present in uid or particle form. The temperature of thermal degradation in the wood constituents hemicelluloses, cellulose, and lignin ranges from 180 to 300 C, 260 to 350 C, and 300 to 500 C, respectively. The temperature in the glowing zone may even reach up to 900 C. The numerous components of the smoke differ in chemical and physical properties. The gases and low-boiling compounds constitute the gaseous phase, while the higher boiling ones are dispersed in the form of uid droplets or solid particles. The mass of the dispersed phase makes up about 90% of the total mass of the smoke. The proportion of different smoke constituents in both phases depends not only on their chemical composition, but also on the conditions of smoke generation and the temperature and turbulence in the duct leading from the generator to the smokehouse. Cooling increases the weight proportion of the higher boiling compounds, while heating raises the concentration of vapors. Brownian motion leads to

Although the alpha-delta sleep abnormality is not speci c to FM, as it has been observed in individuals without FM, it may represent a source of vulnerability to development of FM under favorable circumstances, especially considering that stage 4 sleep is a time of neurohormonal and neurotransmitter restoration (Bennett, 1993) Unlike OA and RA, which are diseases that affect the joints, FM is characterized by widespread pain in soft tissue Pain appears to be particularly noxious at speci c tender points distributed throughout the body To receive a diagno sis of FM, an individual must experience widespread pain in all four quadrants of the body and especially pronounced pain in at least 11 of 18 tender point spots (Wolfe et al, 1990) Other common symptoms of FM include fatigue, stiffness, and depression (Bennett, 1993; Wolfe et al, 1990).

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There remains considerable controversy surrounding the course and prognosis for this condition Although FM symptoms tend to be chronic, there is substantial individual.

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